Seizures and Mood INstability


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The Treatment of Seizures and Mood Instability

Approximately 15-20% of males with FXS have seizures; therefore, the medical history should always include questions concerning possible seizures (Musumeci et al. 1999). Although many seizures are grand mal or generalized tonic-clonic events, other episodes may be partial complex or partial motor seizures with subtle jerking of the face or hand associated with staring, sensory sensations, or guttural sounds. These episodes may be difficult to recognize as seizures, and careful questioning is necessary. Abruptly violent episodes that are not precipitated by environmental stimuli may be temporal lobe or partial complex seizures. If there are clinical questions about the possibility of seizures, an EEG is warranted (chap. 1).

The Treatment of Seizures and Mood Instability: Continued

This article is not intended to give medical advice for individual cases. Any change in medical treatment should be done in consultation with appropriate medical personnel. This article is written for medical professionals. Some of the terms will be unfamiliar to those who are not trained in medical fields.

*This article is from the chapter on treatment in the 3rd edition of Fragile X Syndrome: Diagnosis, Treatment, and Research edited by Randi Jenssen Hagerman, M.D. and Paul Hagerman, M.D., Ph.D., to be published May 2002. It is included with permission from The Johns Hopkins University Press. References to other chapters refer to chapters in the book which are not included as part of this website.

The complete 3rd edition of Fragile X Syndrome: Diagnosis, Treatment, and Research can be ordered from the National Fragile X Foundation by calling 1-800-688-8765 or from The Johns Hopkins University Press at 1-800-537-5487.

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